Thyroid Problems
Still struggling with thyroid symptoms despite "normal" lab results and medication? Your dysregulated nervous system might be the missing piece preventing your thyroid from functioning optimally.
Why don't I feel better despite treatment?
What many practitioners miss is the critical connection between your nervous system and thyroid function. When your nervous system is dysregulated, it directly impacts thyroid hormone production, conversion, and cellular response—even when medication levels appear adequate. This shows up as:
- Persistent fatigue despite "optimal" thyroid hormone levels
- Unexplained weight changes resistant to diet and exercise
- Brain fog and concentration difficulties
- Temperature dysregulation and cold intolerance
- Mood swings, anxiety, or depression that's attributed to "just thyroid issues"
Guide to Nervous System Regulation:
How to regulate your body's operating system for better sleep, digestion, mental clarity and emotional balance
Get free guideNervous system dysregulation disrupts thyroid function
Thyroid problems are exacerbated when you're stuck in Sympathetic Dominance (fight or flight). This creates a cycle of hormonal dysfunction through the following mechanisms:
HPA-Thyroid Axis Disruption
Problem ➜ Chronic stress activates the hypothalamic-pituitary-adrenal (HPA) axis, which directly interferes with the hypothalamic-pituitary-thyroid (HPT) axis. This creates a physiological pattern where stress hormones inhibit proper thyroid function at multiple levels.
Symptom ➜ Thyroid symptoms that worsen during stressful periods—like that energy crash and brain fog that predictably follows high-stress weeks.
T4 to T3 Conversion Impairment
Problem ➜ Stress hormones like cortisol inhibit the conversion of inactive T4 to active T3 thyroid hormone in peripheral tissues. This means even with adequate T4 (from medication or your own thyroid), your cells aren't getting the active T3 they need.
Symptom ➜ Continuing to experience hypothyroid symptoms despite "normal" TSH and T4 levels on blood tests.
Cellular Thyroid Resistance
Problem ➜ Chronic inflammation from ongoing stress creates cellular resistance to thyroid hormones, similar to insulin resistance. Your cells become less responsive to the thyroid hormone that is available.
Symptom ➜ The frustrating experience of taking the right medication but still feeling symptomatic, with doctors unable to explain why.
Autoimmune Triggering
Problem ➜ Nervous system dysregulation increases inflammatory cytokines that can trigger or worsen autoimmune responses like Hashimoto's thyroiditis, where the immune system attacks the thyroid gland.
Symptom ➜ Unpredictable symptom flares and the gradual progression of thyroid destruction despite medication management.
Gut Dysfunction
Problem ➜ Chronic stress impairs gut function, which is critical for thyroid hormone conversion (approximately 20% of T4 to T3 conversion occurs in the gut) and the absorption of nutrients essential for thyroid health.
Symptom ➜ Digestive symptoms that fluctuate alongside thyroid symptoms, and inadequate response to thyroid medication despite dose adjustments.
Metabolic Downregulation
Problem ➜ Persistent stress signals to the body that resources need to be conserved, causing a protective downregulation of metabolism through reduced thyroid function.
Symptom ➜ The classic pattern of unexplained weight gain or inability to lose weight despite diet and exercise efforts.
The hidden cost of thyroid dysfunction
Thyroid problems extend far beyond the physical symptoms, affecting nearly every aspect of life:
70%
of patients with treated hypothyroidism still report significant fatigue that impacts daily functioning
60%
of individuals with thyroid disorders experience mood disorderslike anxiety and depression
69%
increased risk of cognitive impairment over time
78%
of hypothyroid patients report persistent symptoms despite having "normal" lab values
38%
reduction in quality of life compared to healthy controls
Break the cycle
Our science-based programs address thyroid conditions by targeting the nervous system-endocrine connection through:
- HRV training to improve autonomic nervous system balance
- Anti-inflammatory diet
- Gut healing protocols to enhance thyroid hormone conversion
- Stress regulation practices that support the entire endocrine system
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Backed by our research team
Lucy Oliver
MSci, Chemistry & Founder
Dr. Jay Luther
MD,Internal medicine (Harvard)
Dr. Aaron Roughan, DC
CHIROPRACTOR & Behavioural Psychologist
Paola Encinas
NEUROSCIENTIST & BIOMEDICAL ENGINEER
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